NutriDB
Back to Research
Potassium2026-07

Effects of magnesium taurate-potassium citrate on blood pressure and vascular stiffness in low-risk adults with elevated blood pressure.

Dereli SeçkinMagnesium research

Summary

A study found that a supplement combining magnesium and potassium, along with lifestyle advice, helped lower blood pressure and improve artery health in adults with slightly high blood pressure. This suggests it could be a non-drug option for managing blood pressure in this group, offering a potential way to support cardiovascular well-being.

AI-generated summary — read the original

Key points

  • A supplement containing magnesium and potassium was studied for its effects on blood pressure.
  • Participants with elevated blood pressure who took the supplement saw their blood pressure levels decrease.
  • The supplement also appeared to improve the stiffness of their arteries.
  • This approach, combined with lifestyle changes, might offer a non-drug option for managing slightly high blood pressure.

What the study looked at

What question did the study ask? Researchers wanted to know if a specific supplement, combining magnesium taurate and potassium citrate, could help lower blood pressure and improve artery health in adults who had slightly high blood pressure but were otherwise at low risk for heart problems. They also looked at whether it could be a non-drug option when combined with lifestyle advice. How was it studied? This was an observational study involving 121 adults with elevated blood pressure or early-stage hypertension who chose not to take blood pressure medication. All participants received general lifestyle counseling and took the magnesium-potassium supplement daily for three months. The study then tracked changes in their blood pressure (at work, at home, and over 24 hours) and measures of arterial stiffness. What did it find? After three months, participants showed significant reductions in their blood pressure readings across all measurements. Their arteries also became less stiff. The supplement was well-tolerated, with no serious side effects reported. This suggests that magnesium and potassium supplementation, alongside lifestyle changes, might be a safe and effective way to manage elevated blood pressure in low-risk individuals.

Dietary takeaway

This study suggests that increasing your intake of potassium, potentially alongside magnesium, could be beneficial for managing slightly elevated blood pressure. While this study used a supplement, many foods like fruits (bananas, oranges), vegetables (spinach, potatoes), and legumes are naturally rich in potassium. Remember, this was one observational study, so more research is needed to confirm these findings definitively before making major dietary changes based solely on this.

Abstract

Elevated blood pressure (BP) is a key modifiable cardiovascular risk factor. In low-risk individuals, guidelines recommend lifestyle interventions before pharmacotherapy. Evidence for magnesium taurate-potassium citrate supplementation in this setting is lacking. This prospective, single-arm observational study enrolled 121 adults with elevated BP or stage 1 hypertension and low cardiovascular risk (SCORE2/SCORE2-OP), per 2024 ESC guidelines, who declined antihypertensive drugs. All received lifestyle counselling plus magnesium taurate-potassium citrate (121 mg elemental magnesium, 180 mg elemental potassium daily) for three months. The per-protocol cohort included 110 patients. Primary outcomes were BP changes at work, at home (HBPM), and ambulatory BP (ABPM). Secondary outcomes were pulse-wave velocity (PWV), augmentation index (AIx), renal function, and serum electrolytes. At three months, BP at work fell by -12/-9 mmHg, HBPM by -11/-8 mmHg, and ABPM by -11/-8 mmHg (all p<0.001). PWV and AIx improved by -0.9 m/s and -4.0% (p<0.001). Serum magnesium rose by +0.1 mg/dL (p=0.003) without changes in sodium, potassium, or renal function. No serious adverse events occurred. In low-risk adults with elevated BP, magnesium taurate-potassium citrate plus lifestyle advice significantly reduced BP and arterial stiffness over three months, supporting magnesium taurate-potassium citrate as a safe non-pharmacological option. As this was a single-arm observational study with routine lifestyle counselling, causal inference was limited, underscoring the need for randomized trials.

Source: PubMed (PMID: 42439043). AI summaries are for informational purposes only and do not constitute medical advice.