持続可能な食生活パターンの受容性と健康関連指標への影響：パイロット無作為化比較クロスオーバー研究の結果
Acceptability and impact on health-related markers of a sustainable dietary pattern: results from a pilot randomized controlled cross-over study.
Vinelli Valentina, Tucci Massimiliano, Martini Daniela, Rendine Marco ほか — European journal of nutrition
AI要約
このパイロット研究では、持続可能な植物ベースの食事（EAT-IT）が9人の参加者の健康に与える影響を調べました。6週間のEAT-IT食は、食物繊維摂取量の増加と、空腹時インスリンの減少などインスリン感受性マーカーの改善をもたらしました。概ね受け入れられましたが、豆類の調理に手間がかかると感じる参加者もいました。これらの結果は、持続可能な食生活の潜在的な健康上の利点と実用的な課題を示唆しており、より大規模な研究の必要性を強調しています。
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Abstract（原文）
PURPOSE: Well-balanced plant-based diets can promote health and reduce environmental impact. However, evidence from interventional studies remains limited. This pilot intervention study aimed to provide exploratory insights into potential challenges associated with the EAT-IT dietary pattern, an adaptation of the EAT-Lancet Healthy Reference Diet. METHODS: Nine subjects (mean age 26 ± 2 years, 5 females) participated in a 6-week randomized controlled cross-over trial. Participants followed two isocaloric interventions: the EAT-IT dietary pattern and a control diet based on the Italian Food-Based Dietary Guidelines. Dietary intake was recorded using 7-day food records. Anthropometric measurements and metabolic parameters were collected according to standardized and validated protocols. Gut microbiota was analyzed through 16 S rRNA gene sequencing and taxonomic profiling. Acceptability was evaluated via a validated questionnaire. RESULTS: Nutritional analysis showed that the EAT-IT pattern significantly increased fiber intake from 11.3 ± 5.2 to 15.1 ± 4.2 g/1000 kcal and ω-6 fatty acid intake from 5.7 ± 2.2 to 6.6 ± 1.9 g/day (p < 0.05 for interaction). Regarding metabolic markers, a significant within-group reduction (p < 0.05) was observed for fasting insulin (8.4 ± 2.2 to 6.5 ± 2.2 µU/mL) and HOMA1-IR (2.0 ± 0.6 to 1.5 ± 0.5). Changes in gut microbiota were also observed, specifically an increase in Bacteroides and a decrease in Coriobacteriaceae. While generally well-accepted, participants reported a higher perceived effort for EAT-IT, particularly regarding legume preparation. CONCLUSION: Despite the small sample size, this pilot study offers relevant insights into key aspects of sustainable plant-based diets, underscoring the necessity for further investigation.
出典: PubMed (PMID: 42319445)。AI要約は情報提供のみを目的とし、医療的アドバイスを構成するものではありません。