アルコール摂取と大腸がん発生の見直し：食事と腸内細菌叢の視点
Rethinking ethanol consumption and colorectal carcinogenesis: an insight from diet and gut microbiota.
Gómez-Pérez Eva, Ruiz-Saavedra Sergio, Zapico Aida, Suárez Adolfo ほか — Frontiers in cellular and infection microbiology
AI要約
大腸がんは生活習慣に強く影響され、アルコール摂取は重要な危険因子です。本稿では、食事、腸内細菌叢、宿主の相互作用が、アルコールの有害な影響と大腸がんとの関連をどのように媒介するかを探ります。この複雑な関係を理解することは、大腸がんの予防と管理において極めて重要です。
AI生成の要約です — 原文を読む
Abstract（原文）
Colorectal cancer (CRC) is a pathology highly influenced by lifestyle and dietary habits, with ethanol consumption recognized as one of the most impactful and modifiable risk factors. Intestinal microbiota alterations have been observed both in high alcohol consumers and in the progression of intestinal polyps to CRC. The diet-microbiota-host interplay has a key role in health and disease. This perspective critically evaluates the mechanistic interplay within this triad and its potential role in mediating alcohol-induced toxicity, as well as its implications for the etiological link between alcohol consumption and CRC risk. Furthermore, we synthesize current advances and delineate key challenges for future research in this area. A particular focus is posed on the analysis of the anatomopathological, nutritional and microbiota data collected from individuals with intestinal polyps in a pilot study carried out in the region of Asturias, Northern Spain.
出典: PubMed (PMID: 42312037)。AI要約は情報提供のみを目的とし、医療的アドバイスを構成するものではありません。