トルコにおけるビタミンD欠乏症の評価、予防、治療に関する最善の実施推奨事項：食品への強制的な強化が限定的な状況における2026年改訂版
Best Practice Recommendations for the Assessment, Prevention and Treatment of Vitamin D Deficiency in Türkiye: A 2026 Update in a Setting with Limited Mandatory Food Fortification.
Gogas Yavuz Dilek, Topaloğlu Ömercan, Güneş Mutlu, Gürlek Alper ほか — Nutrients
AI要約
この専門家合意は、食品強化が限られるトルコにおける成人ビタミンD欠乏症の最新管理推奨です。欠乏レベルを定義し、集団スクリーニングではなく高リスク者への標的検査を推奨。予防、治療、モニタリングの根拠に基づいたアプローチを提示し、過小治療と過剰使用を避け、適切なケアを目指します。
AI生成の要約です — 原文を読む
Abstract（原文）
BACKGROUND: Vitamin D deficiency is a common global health problem and remains highly prevalent in Türkiye, where limited food fortification and heterogeneous clinical practices contribute to variability in testing and supplementation strategies. AIMS: To provide Türkiye-specific best practice recommendations for defining clinically relevant serum 25-hydroxyvitamin D [25(OH)D] thresholds, identifying adult risk groups for targeted testing, and recommending evidence-based prevention, treatment, and monitoring approaches while minimizing under-treatment and inappropriate high-dose use. METHODS: This national expert consensus document was developed by endocrinologists from across Türkiye using a structured, modified Delphi methodology. Draft statements informed by systematic literature reviews were rated via online surveys using a 9-point Likert scale, followed by two Delphi rounds and a face-to-face consensus meeting in İstanbul in October 2025. RESULTS: Recommendations addressed sun exposure, laboratory assessment, screening, supplementation, treatment, and follow-up. Serum 25(OH)D <20 ng/mL was defined as deficiency and <12 ng/mL as severe deficiency, with a target range of 20-50 ng/mL. Routine population-wide screening was not recommended; instead, targeted testing in high-risk adults and symptom-driven biochemical evaluation were endorsed. Empiric supplementation was recommended for selected high-risk groups, with cholecalciferol as the preferred agent. Higher individualized doses were suggested in obesity or malabsorption, while loading regimens were reserved for specific clinical indications, such as severe deficiency or certain medical conditions that impair vitamin D metabolism. Reassessment of 25(OH)D at 8-12 weeks was recommended. CONCLUSION: These consensus-based recommendations provide a practical, context-specific framework for assessing, preventing, treating, and monitoring vitamin D deficiency in adults in Türkiye.
このコラムに関連する書籍
ビタミンD不足が招く病気――骨・免疫・うつに効く正しい補充法
骨代謝・予防医学関連書籍
ビタミンD欠乏の実態と健康への影響を最新研究で解説。食事・日光浴・サプリの正しい使い分けも紹介。
Amazonで本を見るビタミンDが摂れる魚・きのこレシピ
管理栄養士監修
鮭・さんま・しいたけなどビタミンDが豊富な食材を使ったレシピを季節ごとに紹介。
Amazonで本を見るAmazonのアソシエイトとして、栄養DBは適格販売により収入を得ています。
出典: PubMed (PMID: 42280308)。AI要約は情報提供のみを目的とし、医療的アドバイスを構成するものではありません。