生殖年齢の女性における血清25-ヒドロキシビタミンD濃度の有病率と季節変動
Prevalence and Seasonal Variation in Serum 25-Hydroxyvitamin D Concentrations Among Women of Reproductive Age.
Guo Hong-Xia, Zhang Zhi-Hui, Ren Hong-Wei, Wang Hui-Yu — Clinical laboratory
AI要約
この研究により、北京の生殖年齢の女性の92%以上がビタミンD欠乏症であることが明らかになりました。ビタミンDレベルは35歳以上の女性で高く、夏にピークを迎え春に最も低いという季節変動が見られました。研究者らは、妊娠を計画している女性に対し、適切なビタミンDレベルを確保するための定期的な検査を推奨しています。
AI生成の要約です — 原文を読む
Abstract（原文）
BACKGROUND: This study aimed to investigate serum 25-hydroxyvitamin D [25(OH)D] concentrations among women of reproductive age, stratified by age and season, in order to provide information for vitamin D-related health strategies for this population. METHODS: A retrospective analysis was conducted on serum 25(OH)D concentrations in women of reproductive age who underwent preconception health examinations at the Physical Examination Department of Haidian District Maternal and Child Health Care Hospital between December 2022 and December 2024. Participants were stratified by age into two groups: advanced maternal age (≥ 35 years) and typical maternal age (< 35 years). Seasonal categorization included spring, summer, autumn, and winter. Intergroup comparisons were performed, and vitamin D nutritional status was classified based on established thresholds. RESULTS: A total of 2,325 women were included in the study. The mean serum 25(OH)D concentration was 34.45 ± 11.07 nmol/L. Vitamin D deficiency was observed in 92.47% of participants, insufficiency in 6.24%, and sufficiency in only 1.29%. Participants in the advanced maternal age group demonstrated significantly higher serum 25(OH)D concentrations compared to those in the normal maternal age group (p < 0.05). Seasonal variation in serum 25(OH)D concentrations was observed, with the highest levels recorded during summer and the lowest in spring. Concentrations in summer and autumn were significantly higher than those in winter and spring (p < 0.05); however, no significant differences were found between summer and autumn or between winter and spring (p > 0.05). CONCLUSIONS: A high prevalence of vitamin D deficiency was observed among women of reproductive age in Haidian District, Beijing, with significant variations by age and season. Routine assessment of serum 25(OH)D concentrations is recommended for women planning pregnancy to facilitate timely and appropriate vitamin D supplementation strategies.
このコラムに関連する書籍
ビタミンD不足が招く病気――骨・免疫・うつに効く正しい補充法
骨代謝・予防医学関連書籍
ビタミンD欠乏の実態と健康への影響を最新研究で解説。食事・日光浴・サプリの正しい使い分けも紹介。
Amazonで本を見るビタミンDが摂れる魚・きのこレシピ
管理栄養士監修
鮭・さんま・しいたけなどビタミンDが豊富な食材を使ったレシピを季節ごとに紹介。
Amazonで本を見るAmazonのアソシエイトとして、栄養DBは適格販売により収入を得ています。
出典: PubMed (PMID: 42295289)。AI要約は情報提供のみを目的とし、医療的アドバイスを構成するものではありません。