蒸気爆砕および酵素加水分解大豆を含むふりかけ食品による鉄の生体利用率向上：思春期の少女を対象としたランダム化比較試験
Enhancing Iron Bioavailability with Sprinkle Food Containing Steam-Blasted and Enzymatically Hydrolyzed Soybean: A Randomized Controlled Trial in Adolescent Girls.
Laily Noer, Widjayanti Retno Dumilah Esti, Kahfi Jordan, Pangestu Alit ほか — Journal of the American Nutrition Association
AI要約
鉄吸収を高める特殊加工大豆入りふりかけ食品が開発され、思春期少女の試験で、初期鉄不足者の鉄貯蔵量（血清フェリチン）が有意に増加しました。加水分解大豆ペプチドは、特に鉄不足者の鉄状態改善や貧血リスク低減に有望。
AI生成の要約です — 原文を読む
Abstract（原文）
OBJECTIVE: This study extends prior work on soy hydrolysate by developing a sprinkle food formula and evaluating its iron bioavailability and effectiveness in improving iron status among adolescent girls over an eight-week intervention. METHOD: The soybean hydrolysate was produced through sequential steam blasting and enzymatic hydrolysis. It was characterized by its molecular weight distribution-predominantly <15 kDa-and amino acid composition, with high levels of glutamic acid, aspartic acid, and arginine, known for their iron-binding properties. A randomized controlled trial (RCT) was conducted involving 106 female adolescents, comparing serum ferritin levels before and after an eight-week intervention with either the hydrolysate-fortified or control sprinkle product. RESULT: A significant increase in serum ferritin levels was observed among participants with low baseline ferritin (<11 ng/mL) who consumed the soy-hydrolysate-fortified formula, indicating enhanced iron absorption. No significant improvement was detected in participants with normal ferritin but low hemoglobin levels, suggesting that the benefit of soy hydrolysate is more pronounced in individuals with depleted iron stores. Baseline dietary intake and serum profiles were similar between groups, indicating that the benefits observed were likely due to the bioactive properties of soy hydrolysate, especially its amino acid composition and molecular weight that support iron absorption. CONCLUSION: Fortification with hydrolyzed soybean peptides represents a promising strategy to improve iron status and reduce the risk of anemia, while the applied processing method offers an effective, value-added use of agricultural resources.
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出典: PubMed (PMID: 41289521)。AI要約は情報提供のみを目的とし、医療的アドバイスを構成するものではありません。